Studies for People with Type 1 Diabetes (insulin-dependent or IDDM)

Monitoring Autoimmunity in Diabetes

Description: The purpose of the "Monitoring Autoimmunity in Diabetes" study is to look at changes in the body that may occur with the development of type 1 diabetes. The samples taken as part of this study will be used to look at various genes, cells, and factors, which may be associated with type 1 diabetes and the immune system. These will be used to study why some people are at higher risk for developing diabetes and what happens to the immune system with the development of the disease. Participants may also qualify and be asked to participate in a separate clinical study that uses a novel magnetic resonance imaging (MRI) technique to noninvasively image insulitis (the destructive process in the pancreas that leads to loss of insulin production).

Recruitment: Seeking controls (no history of type 1 diabetes) and persons recently diagnosed with type 1 diabetes (within last 6 months). Must be 18 years or older.

Contact: Sarah Szubowicz at (617) 309-4493 or sarah.szubowicz@joslin.harvard.edu

(CHS #2010-27)

The T1D Exchange Type 1 Diabetes Network (Pediatric, Adolescent and Young Adult Section)

Description: This Type 1 Diabetes (T1D) Exchange  is a nationwide registry collecting information about children and adults with type 1 diabetes.  The purpose of the registry is to gather information about people with type 1 diabetes to help better understand the natural course of type 1 diabetes and the effectiveness of current treatments. Participation in the registry involves completion of a questionnaire about medical and family history including diabetes diagnosis and treatment and laboratory test results.  Annual updates of information are also part of the registry.

Recruiting: At the Joslin, individuals being followed in the Pediatric, Adolescent and Young Adult Section may be eligible to participate in this registry.

Contact: Camille Ratliff at (617) 309-4477 or camille.ratliff@joslin.harvard.edu

(CHS #2011-01)